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We will be conducting system maintenance starting on Friday, December 13th, at 6:00 p.m. (ET) through Sunday, December 15th. During this time, many normal functions normally performed on our website, such as placing an order or paying an invoice, will not be available. We apologize for the inconvenience but will have complete return of services on Monday, December 16th.
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CRISPR ToolBox Cells

Researchers developing their own in vitro models via CRISPR genome-editing technology lack ready-to-use tools to quickly, simply, and accurately generate their cell of interest. The do-it-yourselfer must introduce the Cas9 enzyme and then validate its functionality before generating a gene-edited cell line. ATCC now provides researchers an efficient toolbox to accomplish their research needs: stable cell lines that constitutively express the CRISPR Cas9 nuclease. These ready-to-use cell lines enable researchers to carry out CRISPR genome editing and CRISPR interference (CRISPRi) applications with high efficiency, thereby simplifying the genome-editing workflow and getting you closer to data acquisition.





  • Simplified workflow – only sgRNA needed
  • Reduces steps to data aquisition
  • Cas9/dCas9 expression validated
  • Target gene expression knock-down validated
  • Minimal effects on target cell physiology
  • Parental cells available as the ideal control
  • CRISPR-edited Isogenic Cell Lines

    Isogenic Cell Lines

    By utilizing CRISPR/Cas9 gene editing, ATCC offers advanced isogenic cell models with cancer mutations such as the EML4-ALK fusion lung cancer cell line and BRAF inhibitor-resistant melanoma cell lines. These cell lines are ideal in vitro models for anti-cancer drug screening.

    Custom Genome-editing Service

    Custom CRISPR Genome Editing

    ATCC now provides custom genome-editing services that span assay design to cell line development. We will work with you to develop a cell line that best meets your research needs.

    Parental Cell Lines

    Tumor Cell Panels
    Tumor Cells by Source Tissue
    Tumor Cells by Genetic Alteration

    ATCC offers a broad range of tumor cell lines and cell panels that are ideal for tumor biology studies, drug discovery applications, and high-throughput screening.