Tumor Cell Panels
ATCC has designed virtual1 tumor cell panels based on the tissue of tumor origin. Each cell line is further annotated with details regarding known mutations2 in select oncogenes and/or receptors. The application of this data, combined with the size and scope of the ATCC tumor cell line collection, enables more intelligent choices when selecting cell-based research models. These pre-selected panels are powerful tools to accelerate your discoveries in cancer research, drug discovery, compound screening, biomarker selection, pathway analysis and targeted therapeutic development.
1A virtual tumor cell panel provides the convenience of ordering multiple cell lines under the umbrella of a single catalog number. Virtual cell line panels are composed of individual cell lines, shipped simultaneously, but without unified packaging or product sheet. The exception is the ATCC® Breast Cancer Cell Panel, ATCC® No. 30-4500K. The 45 cell lines that comprise the Breast Cancer Cell Panel are packaged together in a kit box.
2The mutation data was obtained from the Sanger Institute Catalogue Of Somatic Mutations In Cancer web site, http://www.sanger.ac.uk/cosmic Bamford et al (2004) The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website. Br J Cancer, 91,355-358. ATCC and The Sanger Institute provide these data in good faith, but make no warranty, express or implied, nor assumes any legal liability or responsibility for any purpose for which the data are used.
Universal Mycoplasma Detection Kit
The Universal Mycoplasma Detection Kit offers a quick and sensitive PCR-based test to detect mycoplasma contaminants in cell culture. All components required for the PCR reaction are provided and have been optimized for amplification. High specificity is obtained through the utilization of a proprietary mix of buffers, dNTPs and thermostable polymerase, combined with universal primers that are specific to the 16S rRNA coding region in the mycoplasma genome. DNA originating from other sources, such as E. coli and human, mouse, hamster, herring sperm, dog or rat genomic DNA, are not amplified. A touchdown PCR regimen increases sensitivity of the assay, along with enhancing specificity.
XTT and MTT Cell Proliferation Assay Kits
The ATCC XTT Cell Proliferation Assay Kit incorporates a second generation tetrazolium salt to help measure cell proliferation, cytotoxicity, and apoptosis in a fast, simple, high-throughput assay format.
The ATCC MTT Cell Proliferation Assay offers a quantitative, convenient method for evaluating a cell population's response to external factors, whether it be an increase in cell growth, no effect, or a decrease in growth due to necrosis or apoptosis.
Download our technical bulletin to compare the two kits.