Design a smarter experiment. The value of tumor cell lines, as research models and drug discovery tools, is greatly enhanced when there is an understanding of the underlying genetic abnormalities that drive their phenotype.

ATCC has designed virtual¹ tumor cell panels based on the tissue of tumor origin. Each cell line is further annotated with details regarding known mutations² in select oncogenes and/or receptors. The application of this data, combined with the size and scope of the ATCC tumor cell line collection, enables more intelligent choices when selecting cell-based research models. These pre-selected panels are powerful tools to accelerate your discoveries in cancer research, drug discovery, compound screening, biomarker selection, pathway analysis and targeted therapeutic development.

Explore the following list of panels and identify those of interest to you. Click on the icon to learn more about each panel or set of panels.

Tissue-Specific Tumor Cell Panels

Breast Cancer Cell Panel	Lung Cancer Cell Panel
Triple-Negative Breast Cancer Cell Panels	Ovarian Cancer Cell Panel
Colon Cancer Cell Panels	Pancreatic Cancer Cell Panel
Liver Cancer Cell Panel

For DNA and RNA  from cell panels, please contact us.

Gene Mutation Lists for Cell Lines

ATCC has created gene mutation lists based on the ATCC tumor cell line collection and known mutation information maintained in the Sanger Institute COSMIC database². These references should provide useful information for researchers using cell based models.

Click on the gene name  to obtain a .PDF document that lists all of the cell lines in the ATCC collection that carry a known mutation in that gene.

¹A virtual tumor cell panel provides the convenience of ordering multiple cell lines under the umbrella of a single catalog number. Virtual cell line panels are composed of individual cell lines, shipped simultaneously, but without unified packaging or product sheet. The exception is the ATCC® Breast Cancer Cell Panel, ATCC® No. 30-4500K. The 45 cell lines that comprise the Breast Cancer Cell Panel are packaged together in a kit box.

²The mutation data was obtained from the Sanger Institute Catalogue Of Somatic Mutations In Cancer web site, http://www.sanger.ac.uk/cosmic Bamford et al (2004) The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website. Br J Cancer, 91,355-358. ATCC and The Sanger Institute provide these data in good faith, but make no warranty, express or implied, nor assumes any legal liability or responsibility for any purpose for which the data are used.